PET/SPECT
A Novel 64Cu-Labeled Probe for Targeted PET Imaging in Breast Cancer
S. Chen, E. Brown, [PI] et al.
J. Nucl. Med. 65(4), 612–621 · 2024
MRG · McMaster University
Advancing
radiochemistry,
imaging & translational science.
Discovering and developing molecular tools that transform imaging, diagnosis, and therapy.
Scroll to explore
What happens here
From discovery to impact.
A modern radiochemistry program spanning probe design, synthesis, imaging, and translation.
Our Research Map
Six themes,
one translational mission.
An integrated approach across chemistry, biology, engineering, and medicine.
Molecular Probe Design
We design molecular tools that target biological processes with imaging and therapeutic relevance.
From molecular signal to image
Watch a tracer become insight.
Live tracer feed
Signal detected
03 · Signal detected
The radiotracer accumulates in specific tissues and produces detectable imaging signal.
Isotope
64Cu
Half-life
12.7 h
Modality
PET
Inside the lab bench
Explore our tools & technologies.
Vial
Radiotracer preparation and measurement.
Flask
Synthesis chemistry and reaction development.
Pipette
Sample handling and experimental setup.
Hot Cell
Shielded environment for radiochemical workflows.
Data
Analysis, validation, and quantitative readouts.
Scanner
Imaging readout and signal reconstruction.
PI
Portrait placeholder
Principal Investigator
[Principal Investigator Name], PhD
McMaster University · Radiochemistry & Radiopharmaceuticals
Leading discovery, advancing imaging, and building collaborative research at the intersection of radiochemistry, molecular imaging, and translational science.
View BiographyOur people
A collaborative & diverse team.
SC
Sofia Chen
PhD Candidate
PET probe development
EB
Ethan Brown
PhD Candidate
Molecular imaging
AS
Ayesha Singh
PhD Candidate
Targeted radionuclide therapy
ML
Michael Lee
MASc Student
Radiochemistry methods
EW
Emma Wilson
MASc Student
Photoacoustic imaging
NM
Noah Martin
Undergraduate
Chemistry co-op
PP
Priya Patel
Undergraduate
Probe synthesis
LO
Liam O'Connor
Undergraduate
Data analysis
Selected publications
Recent research.
Molecular Probes
Pharmacokinetic Imaging of Infection Using a Bacterial Probe in Mice
A. Singh, M. Lee, [PI] et al.
Mol. Pharm. 21(2), 210–219 · 2024
Radionuclide Therapy
Targeted Alpha Therapy of Hypoxic Solid Tumors with 64Cu/67Cu Conjugates
E. Brown, P. Patel, [PI] et al.
Eur. J. Nucl. Med. Mol. Imaging · 2024
Lab life
Conferences, community & milestones.
SNMMI 2024
Lab Retreat — Niagara-on-the-Lake
Lab Holiday Dinner
Research in Action
Part of MRG
McMaster Radiochemistry Group.
We are proud to be part of the McMaster Radiochemistry Group — advancing discovery, training, and translation together.
Visit MRG websiteLab
Our labMRG
GroupMac
McMasterLet's collaborate
Let's collaborate.
We welcome inquiries from students, partners, collaborators, and industry.
Phone
+1 (905) 525-9140
Address
McMaster University
Hamilton, Ontario, Canada
Hamilton, Ontario, Canada
Audience
Students, postdocs, collaborators, and research partners.